Miami Dolphins vs Buffalo Bills - NFL Prediction (2025-09-19)

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Miami Dolphins
vs
Buffalo Bills

Win probabilities

Miami Dolphins
17%
Buffalo Bills
83%

Predicted score

19 - 30
Spread (Team 1 - Team 2): -11.17
Projected total: 49.13

Fair odds (decimal)

Miami Dolphins: 5.88
Buffalo Bills: 1.20

Canadian Moneyline Odds

Miami Dolphins
+560
Buffalo Bills
-909
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Anytime Touchdown Probability

Miami Dolphins
  • De'Von Achane RB49.5%
  • Tyreek Hill WR33.7%
  • Jaylen Waddle WR24.9%
  • Malik Washington WR15.1%
  • Ollie Gordon RB14.4%
  • Darren Waller TE11.7%
  • Nick Westbrook-Ikhine WR11.3%
  • Julian Hill TE9.3%
  • Jaylen Wright RB6.1%
  • Tua Tagovailoa QB5.3%
  • Alec Ingold FB3.7%
  • Dee Eskridge WR3.5%
Buffalo Bills
  • James Cook RB56.7%
  • Josh Allen QB53.6%
  • Keon Coleman WR29.6%
  • Khalil Shakir WR23.2%
  • Joshua Palmer WR21.2%
  • Dalton Kincaid TE19.2%
  • Ray Davis RB16.6%
  • Ty Johnson RB16.0%
  • Dawson Knox TE13.5%
  • Curtis Samuel WR8.2%
  • Elijah Moore WR6.6%
  • Jackson Hawes TE4.6%

First Touchdown Probability

Miami Dolphins
  • De'Von Achane RB11.2%
  • Tyreek Hill WR6.8%
  • Jaylen Waddle WR4.7%
  • Malik Washington WR2.7%
  • Ollie Gordon RB2.6%
  • Darren Waller TE2.0%
  • Nick Westbrook-Ikhine WR2.0%
  • Julian Hill TE1.6%
  • Jaylen Wright RB1.0%
  • Tua Tagovailoa QB0.9%
  • Alec Ingold FB0.6%
  • Dee Eskridge WR0.6%
Buffalo Bills
  • James Cook RB13.7%
  • Josh Allen QB12.6%
  • Keon Coleman WR5.7%
  • Khalil Shakir WR4.3%
  • Joshua Palmer WR3.9%
  • Dalton Kincaid TE3.5%
  • Ray Davis RB3.0%
  • Ty Johnson RB2.9%
  • Dawson Knox TE2.4%
  • Curtis Samuel WR1.4%
  • Elijah Moore WR1.1%
  • Jackson Hawes TE0.8%

Projected Miami Dolphins Boxscore

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Projected Buffalo Bills Boxscore

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Miami Dolphins vs. Buffalo Bills: Game Breakdown

Matchup details

  • Teams: Miami Dolphins vs. Buffalo Bills
  • Date: loading...
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Betting insights

Spread: Miami Dolphins favored at -11.17. Total: 49.13.

Game prediction summary

Miami Dolphins and Buffalo Bills face off on loading..., loading..., in a matchup that's drawn attention from bettors and fans alike.

We're projecting a final score of Miami Dolphins 19 – 30 Buffalo Bills, with win probabilities leaning 83% in favor of Buffalo Bills. Current odds list the spread at -11.17, with the total set at 49.13.

Touchdown Scorer Predictions

For Anytime Touchdown Scorer bets, the top option from Miami Dolphins is De'Von Achane (the player with the highest anytime touchdown probability on the team at 49.5%). He is followed by Tyreek Hill, who also poses a strong scoring threat with a 33.7% chance.

On the Buffalo Bills side, James Cook leads with the highest probability at 56.7% , while Josh Allen follows closely at 53.6% .

For First Touchdown Scorer odds, our data again puts De'Von Achane (team-high 11.2% probability) as the most likely to score first for Miami Dolphins. Over on the Buffalo Bills side, James Cook ranks highest with a 13.7% chance to be the first touchdown scorer in the game.

Box Score Predictions

When box score data is available, we spotlight each team's leaders by projection. For Miami Dolphins, De'Von Achane (highest projected rusher on Miami Dolphins) is forecast for 59 rushing yards and 0.50 TDs , while Tyreek Hill (highest projected receiver on Miami Dolphins) is pegged for 70 receiving yards and 0.34 TDs .

On Buffalo Bills, James Cook (highest projected rusher on Buffalo Bills) leads the ground game with 72 yards and 0.57 TDs , and Keon Coleman (highest projected receiver on Buffalo Bills) tops the passing attack with 48 yards and 0.30 TDs .

All stat lines are simulation-driven and update as new information becomes available.

Responsible betting

Sports betting should always be fun - a form of entertainment, not a way to solve financial problems. If you're finding that betting is causing stress or impacting your budget, take a step back. Never wager more than you can afford to lose.

Your mental well-being matters. Chasing losses or trying to "win it all back" is a warning sign. If friends or family raise concerns, take them seriously - they're often the first to notice when something's wrong.

If betting no longer feels like a choice or if it's affecting your life in a negative way, help is available. Visit Gambling Therapy for free, confidential support. Their trained advisors are available 24/7, and you'll also find peer support groups to talk with others who understand what you're going through.

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