Jacksonville Jaguars vs Indianapolis Colts - NFL Prediction (2025-12-28)

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Jacksonville Jaguars
vs
Indianapolis Colts

Win probabilities

Jacksonville Jaguars
45%
Indianapolis Colts
55%

Predicted score

22 - 23
Spread (Team 1 - Team 2): -1.35
Projected total: 45.20

Fair odds (decimal)

Jacksonville Jaguars: 2.22
Indianapolis Colts: 1.82

Moneyline (American)

Jacksonville Jaguars: +122
Indianapolis Colts: -122

Jacksonville Jaguars vs. Indianapolis Colts: Game Breakdown

Matchup details

  • Teams: Jacksonville Jaguars vs. Indianapolis Colts
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Betting insights

Spread: Jacksonville Jaguars favored at -1.35. Total: 45.20.

Game prediction summary

Jacksonville Jaguars and Indianapolis Colts face off on loading..., loading..., in a matchup that's drawn attention from bettors and fans alike.

We're projecting a final score of Jacksonville Jaguars 22 – 23 Indianapolis Colts, with win probabilities leaning 55% in favor of Indianapolis Colts. Current odds list the spread at -1.35, with the total set at 45.20.

Responsible betting

Sports betting should always be fun - a form of entertainment, not a way to solve financial problems. If you're finding that betting is causing stress or impacting your budget, take a step back. Never wager more than you can afford to lose.

Your mental well-being matters. Chasing losses or trying to "win it all back" is a warning sign. If friends or family raise concerns, take them seriously - they're often the first to notice when something's wrong.

If betting no longer feels like a choice or if it's affecting your life in a negative way, help is available. Visit Gambling Therapy for free, confidential support. Their trained advisors are available 24/7, and you'll also find peer support groups to talk with others who understand what you're going through.

Bet smart. Stay in control. Your well-being comes first.