Buffalo Bills vs Cleveland Browns - NFL Prediction (2025-12-21)

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Buffalo Bills
vs
Cleveland Browns

Win probabilities

Buffalo Bills
79%
Cleveland Browns
21%

Predicted score

25 - 17
Spread (Team 1 - Team 2): 8.09
Projected total: 42.66

Fair odds (decimal)

Buffalo Bills: 1.27
Cleveland Browns: 4.76

Moneyline (American)

Buffalo Bills: -376
Cleveland Browns: +376

Buffalo Bills vs. Cleveland Browns: Game Breakdown

Matchup details

  • Teams: Buffalo Bills vs. Cleveland Browns
  • Date: loading...
  • Time: loading...

Betting insights

Spread: Cleveland Browns favored at -8.09. Total: 42.66.

Game prediction summary

Buffalo Bills and Cleveland Browns face off on loading..., loading..., in a matchup that's drawn attention from bettors and fans alike.

We're projecting a final score of Buffalo Bills 25 – 17 Cleveland Browns, with win probabilities leaning 79% in favor of Buffalo Bills. Current odds list the spread at -8.09, with the total set at 42.66.

Responsible betting

Sports betting should always be fun - a form of entertainment, not a way to solve financial problems. If you're finding that betting is causing stress or impacting your budget, take a step back. Never wager more than you can afford to lose.

Your mental well-being matters. Chasing losses or trying to "win it all back" is a warning sign. If friends or family raise concerns, take them seriously - they're often the first to notice when something's wrong.

If betting no longer feels like a choice or if it's affecting your life in a negative way, help is available. Visit Gambling Therapy for free, confidential support. Their trained advisors are available 24/7, and you'll also find peer support groups to talk with others who understand what you're going through.

Bet smart. Stay in control. Your well-being comes first.