New England Patriots vs Buffalo Bills - NFL Prediction (2025-10-06)

Kickoff: loading... Starting soon
New England Patriots
vs
Buffalo Bills

Win probabilities

New England Patriots
25%
Buffalo Bills
75%

Predicted score

19 - 27
Spread (Team 1 - Team 2): -7.26
Projected total: 46.14

Fair odds (decimal)

New England Patriots: 4.00
Buffalo Bills: 1.33

Moneyline (American)

New England Patriots: +300
Buffalo Bills: -300

New England Patriots vs. Buffalo Bills: Game Breakdown

Matchup details

  • Teams: New England Patriots vs. Buffalo Bills
  • Date: loading...
  • Time: loading...

Betting insights

Spread: New England Patriots favored at -7.26. Total: 46.14.

Game prediction summary

New England Patriots and Buffalo Bills face off on loading..., loading..., in a matchup that's drawn attention from bettors and fans alike.

We're projecting a final score of New England Patriots 19 – 27 Buffalo Bills, with win probabilities leaning 75% in favor of Buffalo Bills. Current odds list the spread at -7.26, with the total set at 46.14.

Responsible betting

Sports betting should always be fun - a form of entertainment, not a way to solve financial problems. If you're finding that betting is causing stress or impacting your budget, take a step back. Never wager more than you can afford to lose.

Your mental well-being matters. Chasing losses or trying to "win it all back" is a warning sign. If friends or family raise concerns, take them seriously - they're often the first to notice when something's wrong.

If betting no longer feels like a choice or if it's affecting your life in a negative way, help is available. Visit Gambling Therapy for free, confidential support. Their trained advisors are available 24/7, and you'll also find peer support groups to talk with others who understand what you're going through.

Bet smart. Stay in control. Your well-being comes first.