San Francisco 49ers vs Los Angeles Rams - NFL Prediction (2025-10-03)

San Francisco 49ers vs. Los Angeles Rams: Game Breakdown

Matchup details

• Teams: San Francisco 49ers vs. Los Angeles Rams
• Date: loading...
• Time: loading...

Betting insights

Spread: San Francisco 49ers favored at -1.03. Total: 46.66.

Game prediction summary

San Francisco 49ers and Los Angeles Rams face off on loading..., loading..., in a matchup that's drawn attention from bettors and fans alike.

We're projecting a final score of San Francisco 49ers 23 – 24 Los Angeles Rams, with win probabilities leaning 54% in favor of Los Angeles Rams. Current odds list the spread at -1.03, with the total set at 46.66.

Responsible betting

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